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For GSK, making Zejula work in wider population groups will be critical in justifying the high price it is paying. Walmsley, who took over in April 2017, has made replenishing GSK’s medicines cabinet her top priority. She recently hired a business development executive from Roche’s Genentech, another signal of her readiness to make acquisitions. “This is an example of us executing on what we said we were going to do pioneer cufflinks history uk online. to bring growth, pipeline, commercial capability and near-term catalysts,” she told reporters..

“We still will be open to other potential bolt-ons in business development,” Walmsley added pioneer cufflinks history uk online. GSK said buying Tesaro would weigh on adjusted earnings for the first two years by mid to high single digit percentage rates, but the acquisition should be accretive by 2022. The deal is expected to complete in the first quarter of 2019. The company’s dividend policy will not be affected by the deal and GSK still expects to pay 80 pence a share in 2018. Zejula’s revenues in its current approved indication as second-line maintenance treatment for ovarian cancer were $166 million in the nine months to September..

Industry analysts, on average, expect annual Zejula sales to reach $1 billion by 2023, according to Refinitiv data. In addition to Zejula, Tesaro also has several oncology medicines in development, including a number of experimental immunotherapy treatments pioneer cufflinks history uk online. That dovetails with GSK’s other work in cancer, a field where it has had a patchy track record in the past. Three years ago, GSK sold its established cancer medicines to Novartis. But it retained some early-stage projects that it now believes have the potential to leapfrog rivals and be at the forefront of treatment..

NEW YORK (Reuters) – Oil prices jumped nearly four percent on Monday after the United States and China agreed to a 90-day truce in a trade dispute and Canada’s Alberta province ordered a production cut, while exporter group OPEC looked set to reduce supply. Brent crude futures rose $2.23 to settle at $61.69 a barrel, a 3.75 percent gain. U.S. West Texas Intermediate (WTI) crude futures gained $2.02 to settle at $52.95 a barrel, a 3.97 percent increase. Both benchmarks surged more than 5 percent earlier in the session pioneer cufflinks history uk online.

China and the United States agreed during a weekend meeting in Argentina of the Group of 20 leading economies not to impose additional trade tariffs for at least 90 days while they hold talks to resolve existing disputes. The trade war between the world’s two biggest economies has weighed heavily on global trade and sparked concerns of an economic slowdown. Crude oil has not been included in the list of products facing import tariffs, but traders said the positive sentiment was supporting crude markets pioneer cufflinks history uk online.